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A pharmacokinetic study was conducted in rats following oral administration of mildronate at doses of 40160 mg/kg

It is worth noting that, given that each compound is scored by their curated genes involved in each process of oligodendrogenesis (columns G to M), most of the compounds on the upper part of the list (with higher total scores) were identified using the curated genes of several (2 or 3) oligodendrogenic processes (as indicated in column C)

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Anti-Inflammatory Activity: Reduces TNF-alpha-induced IL-6 secretion in human dermal fibroblasts, with proposed anti-inflammatory benefits