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[PMC free article: PMC3413219] [PubMed: 22665167] 423

The most common cause of the disease is the presence of Helicobacter pylori bacteria, which directly affects the gastric glandular epithelium, leading to cell proliferation

Indeed, several studies have reported some level of sex-dependent differences in susceptibility to liver damage

2.2.4 Roles of defensins in abiotic stresses 2.2.4.1 Defensin-mediated mechanisms for heavy metal tolerance A primary mechanism for heavy metal tolerance is the chelation of metal ions by the cysteine-rich domains of defensins, followed by the efflux of the metal-defensin complex from the cytoplasm to less sensitive extracellular compartments like cell walls or the apoplast, or into vascular tissues for transport (Luo et al., 2018