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To study the joint linear relationship of different variables with oxidative stress variables, complementing the correlation analysis, a multiple linear regression model was performed for each oxidative stress variable in R

Lifestyle interventions including proper dietary regimen and moderate exercise can exert marked effect in the early stage of NAFLD, but when the disease progresses to the advanced stages, like fibrosis or cirrhosis, simple lifestyle interventions are unable to achieve satisfactory results, which highly demands the emergence of effective pharmacological agents ( 2

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Unlike previous reviews, this review emphasizes next-generation probiotics, live biotherapeutics, and genetically engineered microbes, and their synergistic interactions with dietary bioactives such as polyphenols and fibers