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Acknowledgments The authors would like to express their sincere appreciation to Clive Chen Clinic, Taichung, Taiwan, and the Department of Neurosurgery, Yuan Rung Hospital, for their valuable support and assistance in the completion of this study

Patients who pair it with sleep, training, nutrition, and the rest of their care see better outcomes than patients chasing one molecule in isolation

Patient-reported outcomes will be important to demonstrate to regulators that many people with T1D can and want to benefit from islet cell replacement therapy, and we need established, systemic methods in place to take the T1D communitys opinions into account

Introduction Parkinsons disease (PD) is the second most common neurodegenerative disease worldwide with 6.1 million patients globally in 2016 (Postuma et al., 2015)