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As many as 5% of patients who end up being diagnosed with vitamin B12 deficiency have blood B12 concentrations above a commonly used cut-off of about 150 mol/L, and even more have abnormal methylmalonic acid (MMA) or homocysteine levels, which are signs of functional B12 deficiency even if overt symptoms are not apparent

These observations make GHK-Cu a useful research tool in neuroprotection, angiogenic signaling, and transcriptomic-response studies

10.1104/pp.109.136630 Plant Physiol

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