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GIP Agonism: Potentiates insulin secretion and regulates lipid storage in adipose tissue

doi: 10.1016/0028-3908(93)90029-3 228 PaulR.JacksonS.WardM.JoshiA.CastroA.YehF

42 (21), e113448

Senolytic compounds can act by inhibiting these proteins, promoting cell death in senescent cells.51,52 For instance, navitoclax (ABT-263), venetoclax, and ABT-737 are BCL-2 inhibitors that disrupt pro-survival signaling, leading to senescent cell death