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Artesunate (ART), a water-soluble hemisuccinate derivative of dihydroartemisinin (DHA), originates from artemisininan active compound isolated from Artemisia annua with extensive traditional Chinese medicinal applications and current use as a frontline antimalarial agent ( 2+ levels, lipid peroxidation, and ferroptosis-related gene expression, while further exploring ferroptosis mechanisms in MM cells and their association with sterol regulatory element-binding protein 2 (SREBP2) nuclear localization

Areas of high interest are imaging and diagnostics, drug delivery and anticancer therapy [17,18,19,20,21,22,23,24,25]

Despite these advances, the structural mechanisms by which proteins interact with rG4s to mediate ribonucleoprotein condensation via LLPT, or how the dynamic behavior of individual LLPT components is regulated, remain poorly understood

used the Broad Institute gene response database The Connectivity Map to identify the top molecules capable of reversing gene expression characteristic for metastatic colon cancer