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Although more than twenty years have passed since its discovery as the leading cause of the cancer syndrome Hereditary leiomyomatosis and Renal Cell Carcinoma (HLRCC), it is still unclear how the loss of FH causes cancer in a tissue-specific manner and with such aggressive behaviour

The Markov clustering identified four distinct clusters, revealing two characteristic groups: a TM-positive and a TM-negative group

For individuals with conditions like pernicious anaemia, an autoimmune disorder that attacks the protein needed to absorb B12, oral supplements are often completely ineffective

At the same time, clinics that focus on hormone replacement therapy often Hormone Replacement Therapy (HRT) has traditionally required in-person consultations, extensive lab work, and regular follow-ups to ensure efficacy and safety