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A: Evening dosing can worsen reflux symptoms in susceptible individuals because delayed gastric emptying increases the likelihood of reflux when lying supine

In conclusion, recent findings on the structural and functional relationships and genetic, physiological, and pharmacological properties of Piezo1 channels have largely contributed to our understanding of CNS mechanics

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Results showed Cerebrolysin was significantly more effective than placebo for cognitive function at 4 weeks (SMD -0.40, p=0.003), global clinical change at both 4 weeks (OR 3.32, p=0.02) and 6 months (OR 4.98, p=0.015), and combined global benefit (cognitive + clinical) at both timepoints