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SPB Academic, The Hague, pp 109123 Berthe-Corti L, Hulsch R, Nevries U, Eckardt-Schupp F (1992) Use of batch and fed-batch fermentation for studies on the variation of glutathione content and its influence on the genotoxicity of methyl-nitro-nitrosoguanidine in yeast

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Note that hGPX4-C is a mutant form of hGPX4 with the active site selenocysteine mutated to cysteine (U46C), resulting in much lowered enzyme activity

These stimulate downstream MAPK/ERK and PI3K/AKT signaling, which eases expression of luteal steroidogenic genes, cell survival and progesterone