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Cisplatin is a commonly used drug for treating osteosarcoma, but osteosarcoma cells can develop resistance to it, which reduces its therapeutic effect (190)

HYGIENE A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof A61K2800/92Oral administration Definitions the invention relates to a toothpaste providing a convenient way to enhance the health, well-being, and/or the appearance of the users skin, and to kits, including those that include such toothpastes and methods of their use

Recently, Wangs team discovered that the promoter region of GPX4 binds to cyclic adenosine monophosphate response element binding protein (CREB) and that this binding can be enhanced by E1A binding protein P300 (EP300), promoting tumor proliferation, migration, invasion and angiogenesis

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