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Sufficient calories, sufficient protein

In addition, Fe 2+ is a cofactor of lipoxygenases (LOXs) that catalyzes PUFA-containing phospholipids into pro-ferroptotic lipid peroxidation (Yang et al., 2016)

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This was unexpected as a high GSH level from selection of phenotypically high GSH producers in the pGSH1-URA3 strain population should inhibit the expression of Ura3-GFP when under control of the GSH-regulated pGSH1