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Consequently, mtDNA is prone to various types of damage, including strand breaks and base deamination, among others

This activation induced the expression of pro-fibrotic genes such as -smooth muscle actin and fibronectin, leading to TM fibrosis and obstructed aqueous humor outflow (Wan et al., 2021

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While the average percentage of calories derived from fat has gone down slightly, averagedaily fat intake, in grams, has stayed the same or has gone up