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(100) developed a nano-polymeric drug system (NanoDOPA) to enhance the brain delivery and therapeutic efficacy of L-dopa in a mouse model of PD

Through innovative research, scientists have been testing the use of GSH in Parkinsons disease

A classic pharmacokinetic study in the Annals of Internal Medicine (Levine et al., 2004) found that a modeled 50 g IV dose produced peak plasma levels around 13,400 mol/L, versus 220 mol/L for the maximum tolerated oral regimen roughly 3070 times higher plasma concentrations with IV administration

Howard SC, McCormick J, Pui C-H, Buddington RK, Harvey RD (2016) Preventing and managing toxicities of high-dose methotrexate