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Other choices include calmodulin-binding peptide, Strep-tag (oxtapeptide binding to streptavidini), chitin-binding domain, and FLAG-tag (another octapeptide that binds to anti-FLAG mAbs)

However, their analysis focused primarily on early disease stages and did not functionally resolve upstream regulatory drivers or their metabolic implications, particularly in advanced lipedema [22]

doi:10.1074/jbc.M112.390245 789. Liu T, Li J, Wang X, Huang T, Wu W, Li A, Li C, Huang X, Wang Q, Li D, et al

Most of these quantitative findings come from in vitro and ex vivo models rather than human intervention studies, so their direct clinical relevance remains under investigation