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COX-2 is thought to mediate the protective effect of late ischemic preconditioning through metabolic production of PGE2 and PGI2

Sensitivity analysis shows how this hierarchy shifts under alternate scenarios, such as higher carbon pricing or elevated fertilizer demand

Arginase-1, predominantly expressed in macrophages, and arginase-2, localized in various cells including myofibroblasts, both contribute to proline generation

An older biochemical study demonstrated that a photooxidation product of the plant auxin IAA, 3-methyleneoxindole, can function as an affinity label for pi-class GST and inactivate it, suggesting that certain indole derivatives can engage mammalian GST active sites under experimental conditions