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(PubMed) Woods KL, Fletcher S, Roffe C, Haider Y

Nature 1996, 380, 439442

Hepatocyte-specific deletion of hepatocyte nuclear factor-4 in adult mice results in increased hepatocyte proliferation

Another recent study demonstrated that OS was higher in patients treated with sorafenib (10.7 months) than patients who received the placebo (7.9 months) (Llovet et al., 2008)