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In particular, three human ABC transporters have been implicated in clinical MDR, belonging to the ABCB (ABCB1/MDR1/P-glycoprotein), ABCC (ABCC1/MRP1), and ABCG (ABCG2/MXR/BCRP) subfamilies(Robey et al

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Dosage doesn't work like that here consistency at a moderate dose beats an aggressive dose taken inconsistently, every time

It is widely recognized that brief episodes of ER stress trigger the unfolded protein response (UPR), which helps safeguard cells from the harmful effects of misfolded and unfolded protein accumulation