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[PubMed ID: 18484280]

Existing genetic vaccine vectors have not been optimized for human tissue, providing low and short-lasting expression of the antigen of interest, with insufficient stability, inducibilitv, or levels of expression in vivo, among other things Largely due to the lack of suitable laboratory models, none of the existing genetic vaccine vectors have been optimized for human tissues

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Supplementation with centella asiatica appeared to improve signs and symptoms and hand flexibility, possibly by collagen remodulation