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Following the finding that the cancer cell lines did not elevate telomerase enzyme activity upon epitalon treatment but did elongate telomeres, we investigated the other commonly used mechanism to extend telomeres in mammals, ALT (Alternative Lengthening of Telomeres)

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We will provide a concise overview of the production of ROS and the development of OS in the male reproductive tract along with the physiological and pathological effects thereof on male reproductive functions

iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease