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Potentiation of anti-myeloma activity of daratumumab with combination of cyclophosphamide, lenalidomide or bortezomib via a tumor secretory response that greatly augments macrophage-induced ADCP

PLoS One 10 , e0141743, (2015)

As acyl-CoAs are not excreted from cells and are thus not possible to measure directly in plasma or excreta, identification of acyl-CoA dependent metabolites such as amino acid conjugates, acyl carnitines, and metabolites formed through -oxidation can provide insights into acyl-CoA formation and the possible roles in formation of reactive metabolites

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