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Compelling pieces of evidence have shown that n-3 intake, including maternal n-3 consumption, has beneficial effects in alcohol-elicited neurodegeneration, particularly in FASD, and alcoholic liver damage, also improving alcoholic gastric hemorrhage (67), pancreatitis (68) and angiogenesis (55) (Supplementary Table 1)

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Notably, the upregulation of hmgR , which encodes HMG-CoA reductase, a rate-limiting enzyme in the mevalonate pathway, supports previous findings highlighting its crucial role in carotenoid overproduction under metabolic pressure

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