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Among forty COPD patients, only sixteen chose to carry out the 6 months observational study No significant differences were found for cigarette pack/year, Forced Expiratory Volume in 1 s (FEV1) L/%, Forced Vital Capacity (FVC) L/%, Body Mass Index (BMI), within the COPD patient group (Table 2)

Collectively, PA disrupts brain function through neurotransmitter imbalance (GABA/NMDA dysregulation), synaptic dysfunction, and cytoskeletal destabilization

Secondly, continued investigation of effects attributable to specific LCACs is required for understanding the pathophysiological aetiologies of arrhythmias and cardiomyopathies associated with LCACs