glutathione peroxidase 1 brain Mice Deficient in Cellular Glutathione

16 In addition, interactions between the intestine and liver are bidirectional, and hepatogenic inflammatory cytokines thus impair intestinal mucosal barrier function, disrupting tight junctions of the intestinal epithelium, and forming a malignant liver-gut cycle during NAFLD

Pitts MW, Byrns CN, Ogawa-Wong AN, Kremer P, Berry MJ

The brain is particularly susceptible to oxidative stress given its limited antioxidant enzymatic capacity to counteract reactive oxygen species production (Ferreira et al., 2015)

And for skin lightening specifically by directly influencing melanin production, it can help achieve desired pigmentation changes with consistent IV sessions