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Deficiencies or imbalances in thiol-based systems can lead to oxidative damage, neurodegenerative disorders, and metabolic diseases

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Drug screen in SK-MEL-103 with selected electrophilic compounds in combination with cell death inhibitors Selected electrophilic compounds were tested in SK-MEL-103 cells in the presence of apoptosis or ferroptosis inhibitors (emricasan and liproxstatin 1, respectively)

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CrossRef Cardiac Phosphodiesterases Are Differentially Increased in Diabetic Cardiomyopathy Rita Hanna, Wared Nour-Eldine, Youakim Saliba, Carole Dagher-Hamalian, Pia Hachem, Pamela Abou-Khalil, Delphine Mika, Audrey Varin, Magali Samia El Hayek, Latitia Pereira, Nassim Fars, Grgoire Vandecasteele, Aniella Abi-Gerges Life Sciences.2021

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