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Oridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive response

Myeloid-derived suppressor cells (MDSCs) and activated tumor-associated macrophages express ARG1, which consumes arginine to form a microenvironment that is not conducive to T cells, resulting in tumor immunosuppression (Rodriguez et al., 2017

Like NAD+, Glutathione production can naturally decline with age, as well as chronic stress, pollution exposure and poor diet

BPC-157 has attracted interest because of its potential effects on gastrointestinal tissue repair and inflammation, though most research remains preclinical