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Description

Ferroptosis and AD pathology Amyloid (A) plaques and neurofibrillary tangles (NFTs) A plaque accumulation is a hallmark pathological feature of AD, where abnormal A aggregation disrupts synaptic function and impairs memory (30,31)

An interesting question is whether there are feedback loops between ferroptosis and iron homeostasis

A semi-synthetic organism with an expanded genetic alphabet

Saturated fatty acids liberated from LDs, or taken up from circulation into the liver, may directly promote tissue injury, leading to additional macrophage recruitment and activation (121)