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Neutralizing ROS, various antioxidant substances (natural and synthetic) may help to reduce oxidative stress and limit tissue damage in chronic inflammatory conditions

The cerebrovascular adaptations to RT are supported by work from Thomas et al, who conducted 12 weeks of progressive RT (progression from 60%90% 1RM with repetitions lowering as intensity increases, 3 times per week) in healthy young adults and similarly observed increased cerebrovascular resistance and decreased pulsatility at rest

We thoroughly discussed the bidirectional role of ferroptosis in radiotherapy, providing new strategies and insights for improving tumor radiotherapy sensitivity and reducing radiation-induced injury in clinical practice

In vivo studies may be constrained by variations in genetic origins, environmental circumstances, and disease progression in animal models and humans