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In particular, the PI3K/AKT axis converts phosphatidylinositol-4,5-bisphosphate (PIP 2 ) to phosphatidylinositol 3,4,5-trisphosphate (PIP 3 )

[15] Animal model studies with GGC have supported a potential therapeutic role for GGC in both the reduction of oxidative stress induced damage in tissues, including the brain [16] and as a treatment for sepsis