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its holding it back from getting recognition, its holding it back from getting funding and its probably holding back the biomarker hunt big-time

Carbon dots: from synthesis to unraveling the fluorescence mechanism

Similarly, in the Mfn1 and Mfn2 double-knockout mouse model, spermatocytes showed mitochondrial fragmentation and reduced mitochondrial content, abnormal cristae, and lower numbers and activity of OXPHOS subunits (NdufB6 and MTCOI), resulting in obstruction from the leptotene to the pachytene stage, inhibiting spermatogenesis, and leading to a significant decrease in sperm [46]

The specific glycyl-L-histidyl-L-lysine sequence with a copper 2+ complex is what has 50 years of peer-reviewed support behind it