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doi: 10.1016/j.freeradbiomed.2019.05.035 286 ValdsA.Ortega MorenoL.Rojo RelloS.OrduaA.BernardoD.CifuentesA

& Hoffmann, P

Lancet 392 , 27052717 (2018)

As intracellular GSH is exhausted, the GSH synthesis system will be activated accordingly, which would weaken the efficacy of GSH exhaustion-based cancer therapies in long-term treatment (Niu et al., 2021)