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However, oral supplementation of L-arginine, the precursor for NO synthesis, has been shown to be largely ineffective at increasing NO synthesis and/or bioavailability for several reasons, which makes L-citrulline much more ideal for boosting levels of L-arginine and subsequently NO

Cell 166 , 766778 (2016)

In the prevention experiment, all saline treated mice developed tumours at day 10, whereas only half of the mice treated with cGP developed palpable tumours 16 days after inoculation (Fig