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About 3% of participants discontinued due to side effects

Data are lacking from long-term studies to assess whether oral treatment is effective when doses are administered less frequently than daily

According to the United States Food and Drug Administration (FDA), dietary supplements are not monitored for safety or efficacy before hitting the market [6]

As absorption is reduced, body stores become low and a deficiency occurs Underlying diseases most commonly include: IBD (inflammatory bowel disease) Intestinal cancer (especially small cell lymphoma) Liver disease Pancreatitis and other pancreatic diseases Symptoms of low B12 levels Typically found in middle-aged or older cats that present with: Weight loss Diarrhea Vomiting Anorexia Thickened intestines In humans, B12 deficiency may also be associated with dementia, cardiovascular disease, and a certain type of anemia, although these are not specifically recognized problems in cats