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G-actin sequestration Primary function, essential for motility of fibroblasts, keratinocytes, endothelial cells and cardiomyocytes

In this context, the observed abilities of these tested agents to abate MSG-induced elevation in ER stress, oxidative stress and neuroinflammation, cooperatively resulted in hindering MSG-induced neuronal apoptosis, which is supported by anti-apoptotic Bcl-2 upregulation and prop-apoptotic BAX downregulation in these groups compared to MSG-intoxicated group

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