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doi: 10.3389/fimmu.2025.1581928 Received 23 February 2025 Accepted 22 July 2025 Published 11 August 2025 Volume 16 - 2025 Edited by Lu Wang, Jinan University, China Reviewed by Xiaodong Chu, Jinan University, China Aayushi Mahajan, Columbia University, United States Jianlin Zhu, Guizhou Provincial Peoples Hospital, China Updates Copyright 2025 Zhao, Ao, Sorina, Wei, Yin, Zhang, Lee, Du and Zhou

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5.3 Vitiligo Vitiligo involves heightened oxidative stress and iron accumulation, which makes melanocytes highly susceptible to ferroptosis