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10.3109/10799899409101509 J

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(4) Patients with confirmed resistance to entecavir or reduced glutathione, as evidenced by prior treatment failure, documented drug resistance mutations, or lack of clinical response to these drugs in past therapies

Notably, SAMHSA also made updates to their descriptions of initial and periodic assessment activities at 8.12(f)(4), which initially informed the definitions of intake activities and periodic assessments in the definition of OUD treatment services at 410.67(b) and the creation of codes describing these services (HCPCS codes G2076 and G2077) when CMS first implemented the Medicare OTP benefit in the CY 2020 PFS final rule