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Consistent with CMS' response on page 10 of the revised Medicare Part D Drug Inflation Rebate Guidance, we affirm that 428.101(b) does not impose additional reporting requirements on pharmacies related to the exclusion of drugs where the average annual total cost under Part D is less than $100 per individual per year

Interestingly, introduction of carboxylic acid groups to RT slows down its reaction kinetics towards GSH comparing to RT-NH 2 and TQG-CN (Table 2), presumably due to the charge repulsion between the carboxylic acid groups and the anionic GSH

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