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these patients develop rapidly progressive childhood-onset dystoniaparkinsonism, with clinical findings supported by distinctive brain MRI findings and post-mortem evidence of neurodegeneration 52

Along with chemotherapy drugs, it can promote cell repair and flush out toxic substances

-Amyloid peptides enhance -synuclein accumulation and neuronal deficits in a Transgenic mouse model linking Alzheimers disease and Parkinsons disease

For example, pH-sensitive nanoparticles achieve passive targeting through the EPR effect (enhanced permeability and retention effect) in pancreatic cancer models, significantly enhancing drug delivery and reducing toxicity (Yetisgin et al., 2020)