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Real-time imaging reveals local, transient vascular permeability, and tumor cell intravasation stimulated by TIE2 hi macrophage-derived VEGFA

S -nitrosylation of phosphotransfer proteins represses cytokinin signaling

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In severe hypoxia, p53 levels rise more significantly than in mild hypoxia, leading to the degradation of HIF-1 through Mdm2 and ultimately resulting in apoptosis