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Iron can enter the cell via transferrin 1 receptor (TfR1, also known as TFR1) and be reduced from ferric (Fe 3+ ) to ferrous (Fe 2+ ) form via metalloreductase STEAP3 in the endosome (Zhang et al., 2012)

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10.1073/pnas.79.4.1088

A substantial body of research has emerged in recent years, focusing on the role of N6-methyladenine (m6A) RNA modification in glucose, amino acid, and lipid metabolism