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Toxicology (2015) 334:94103

Hz and AcHz are thought to be further oxidized to reactive metabolites and involved in INH hepatotoxicity13, 16, 28, 56, 57, which was proposed to be mediated by microsomal P450s, especially CYP2E56, 58

Phenolic fraction extracted from Kedrostis foetidissima leaves ameliorated isoproterenol-induced cardiotoxicity in rats through restoration of cardiac antioxidant status