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Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia

Finally, sections were counterstained with hemalum, dehydrated and mounted in DPX

The most obvious problem is that immunocompromised people are more susceptible to severe symptoms

Genetic ablation of SEPP1 has been shown to reduce serum Se concentrations by 25-fold but only reduces bone Se levels by 25-fold, suggesting a protective effect (Reference Zhang, Zhang and Xiao18)