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This may include arthroscopic surgery to repair damaged tissue or a full joint replacement in extreme cases

Dopaminergic neurons are the neurons responsible for dopamine production

This creates the soft, teardrop shape many patients desire without the artificial roundness sometimes seen with complete submuscular placement

Nicotinamide and allopurinol seem to be effective in reducing the inflammation of soft tissue but the data sustaining this conclusion were obtained in a rather small sample of GO patients affected with both moderate-to-severe and mild GO ( in vitro results on the use of pentoxifylline are promising, but clinical studies provided conflicting results ( in vitro findings reported above, one can speculate that quercetin and -carotene might be the most promising, but clinical trials are needed to confirm this hypothesis