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As the Figure 7 illustrates, the group treated with the BHE extract showed a TNF level of 8.680.33 pg.mg of protein 1 , which is less than half of the value corresponding to the control group: 19.981.61 pg.mg of protein 1

4.6 ALS Mechanisms Targeted by Current Investigational Agents To identify current ALS investigational agents, we accessed the ClinicalTrials.gov database on 1 October 2024