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Moreover, goldenseal can also inhibit the cytochrome P450 isoforms, including CYP1A2, CYP2D6, CYP2E1, and CYP3A, and the IC 50 values were 15.7, 7.4, 4.3, and 52.1 g/ml in rats, respectively

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The peptide consists of three amino acidsglycine, histidine, and lysinein precise coordination with a copper ion, creating a bioactive complex with remarkable biological activities across diverse physiological systems