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Functionally, PIK3R1 activation can promote protein synthesis and glycogen transportation and induce cell proliferation by regulating the PIK3K-AKT-mTOR signaling pathway

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TMAO Discovery and Structure How TMAO Was Discovered TMAO was first identified in the 19th century as a byproduct of fish decomposition, responsible for the fishy odor when it breaks down into trimethylamine (TMA)

Findings: Steroid hormone biosynthesis pathways, including androstenedione metabolism as well as androgen and estrogen metabolism, were overrepresented by metabolites that significantly discriminated samples in the +ADT from the ADT group