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FXS patients display a variety of intellectual deficits ranging from mild learning impairments to severe cognitive disabilities, but also autistic behaviors such as aggression, social anxiety and stereotypic acting characterize the disease (reviewed in Saldarriaga et al., 2014

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Scientific discussion surrounding MOTS-c (a mitochondrial-derived peptide) commonly highlights its relevance within models of metabolic homeostasis and adaptive cellular responses to stress