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In addition, butyrate can activate the signaling pathway mediated by G protein-coupled receptors (GPRs), further inhibiting the downstream MEK-ERK and NF-B pathways

The decision not to take serum methylnalonic acid and homocysteine concentrations into account as diagnostic markers and outcome variables was made bearing in mind that these are not normally determined, either at diagnosis or during follow-up, in patients with a vitamin B12 deficiency

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These signaling pathways influence endothelial cell communication, angiogenic responses, and cellular survival under oxidative stress conditions