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10.1038/srep45995 80 MiyoshiK.NaritaM.TakatsuM.SuzukiT

Subjects with deep infiltrating endometriosis were the youngest at the time of index operation (35.77.2 years), followed by endometrioma only (37.98.1 years) and adenomyosis only (45.96.7 years)

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When insulin binds to the extracellular domain of IRTK, it induces a conformational change that results in the autophosphorylation of IRTK tyrosine residues and the subsequent activation of phosphotyrosine-binding proteins such as insulin receptor substrate (IRS), growth factor receptor-bound protein-2 (GRB-2), GRB-10, SHC-transforming protein (SHC), and SH2B adapter protein-2 (SH2B-2) [8]