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10.12659/MSM.892597 Summary Keywords lactate shuttle, cancer, HIF-1, NF-B, hypoxia, PHD2 Citation Rastogi S, Aldosary S, Saeedan AS, Ansari MN, Singh M and Kaithwas G (2023) NF-B mediated regulation of tumor cell proliferation in hypoxic microenvironment

Coadministration of curcumin with other phytochemicals improves anticancer activity by regulating multiple molecular targets

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The S-chiral ester of NPAA (S-NPAA) was two-fold more effective than the R-chiral ester (R-NPAA) in depleting GSH, increasing oxidative stress, inducing apoptosis, and decreasing cell viability in tumorigenic prostate LNCaP cells but had little effect on non-tumorigenic RWPE-1 cells